Inflammation And Cardiology

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Efavaleukin alfa
(AMG 592)


IL-2 mutein Fc fusion protein
Phase 2
Monotherapy
Indication
Ulcerative Colitis
A Phase 2, Dose-finding, Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Safety and Efficacy of Efavaleukin Alfa Induction Therapy in Subjects With Moderately to Severely Active Ulcerative Colitis
Amgen protocol ID 20170104
Status Switzerland
Recruiting
Centers, Principal investigators:
KSSG, S. Brand ✉︎
USZ, L. Biedermann ✉︎
Intesto BE, F. Seibold ✉︎
Inselspital, B. Misslewitz ✉︎
Rocatinlimab
(AMG 451)


anti-OX40 Antibody
Phase 3
Combination therapy
+ topical corticosteroids/
topical calcineurin inhibitors
Indication
Atopic dermatitis
rocket-shuttle
A Phase 3, randomized, 24-week, placebo-controlled, double-blind Study to Assess the Efficacy, Safety, and Tolerability of Rocatinlimab in Combination with Topical Corticosteroids and/or Topical Calcineurin Inhibitors in Adult Subjects with Moderate-to-severe Atopic Dermatitis
Amgen protocol ID 20210144
Status Switzerland
Recruiting
Centers, Principal investigators:
KSSG, A. Cozzio ✉︎
USZ, C. Lang ✉︎
Insel, D. Simon ✉︎
CHUV, T. Caplanusi ✉︎
HUG, E. Laffitte ✉︎